Possible Risks and Side Effects
The SCOT research consent form describes the known risks and side effects associated with stem cell transplantation and high-dose monthly Cytoxan. Because these study procedures are investigational and your doctor cannot be sure how your body will respond, you should carefully read the consent form.
Serious side effects, including death, have been associated with these study procedures. These side effects are more likely to occur during the first year after the procedure. Past experience has shown that approximately 5–10% of the individuals who receive autologous (self) stem cell transplant die from transplant complications.
Here are some of the other potential side effects associated with both study procedures. Refer to the SCOT research consent form for a complete list.
- Nausea
- Vomiting
- Mouth or lip sores
- Diarrhea
- Hair loss
- Decreased appetite
- Loss of energy
- Decreased white blood cell counts, which increases your risk of infection
- Increased risk for cancer
- Increased risk for damage to the heart, lungs, brain, kidneys, liver, and/or reproductive organs
- Sterility (unable to have children) — If you would like to have children in the future, please discuss this issue with the SCOT study staff.